Liquoral liquid biopsy in neoplastic meningitis enables molecular diagnosis and mutation tracking: a proof of concept
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Intracranial Fungal Granuloma Mimicking Neoplastic Lesion: Diagnostic Dilemma and Role of Voriconazole as Treatment Strategy
ABSTRACT Fungal infections of the central nervous system (CNS) usually present as subacute meningitis or intracranial space occupying lesion with mass effect on surrounding structures and consequent focal neurological deficits. Intracranial fungal granulomas are often misdiagnosed clinically and radiologically as neoplastic lesions. Biopsy of the lesion is the only reliable technique to estab...
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Molecular characterization of a patient’s tumor to guide treatment decisions is increasingly being applied in clinical care and can have a significant impact on disease outcome. These molecular analyses, including mutation characterization, are typically performed on tissue acquired through a biopsy at diagnosis. However, tumors are highly heterogeneous and sampling in its entirety is challengi...
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عنوان ژورنال:
دوره 19 شماره
صفحات -
تاریخ انتشار 2017